Web1. sep 2024 · Abstract. Purpose To perform a critical analysis on the impact of depth of response in newly diagnosed multiple myeloma (MM). Patients and Methods Data were … Web23. sep 2008 · The outlook for relapsed disease has been significantly improved in early trials using the new agents bortezomib (Rajkumar et al, 2005) and the immunomodulatory drugs (Richardson et al, 2002 ...
Pathema - Wikipedia
Web12. nov 2013 · Methods: The IC-APL treatment protocol is similar to the PETHEMA 2005, but changing idarubicin to daunorubicin. All patients with a suspected diagnosis of APL were immediately started on ATRA, while bone marrow samples were shipped to a national central lab where genetic verification of the diagnosis was performed. The … Web1. dec 2005 · High-dose therapy intensification compared with continued standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: long … primary education stirling
Superiority of bortezomib, thalidomide, and dexamethasone (VTD) …
Web24. jún 2010 · A risk-adapted strategy based on all- trans retinoic acid (ATRA) and anthracycline monochemotherapy (PETHEMA LPA99 trial) has demonstrated a high … Fluorescence in situ hybridization analysis were available in 230 (85%) of the 271 patients randomized to receive maintenance therapy. Thirty-five of these 230 patients (15%) had high-risk cytogenetics and were similarly distributed among the three maintenance arms: 14 patients were treated with alfa2-IFN, 9 … Zobraziť viac Between 6 April 2006 and 5 August 2009, the 390 planned patients were included in the study. A total of 283 patients received the six planned induction … Zobraziť viac A response improvement during maintenance therapy was observed in 20% of the patients. The median time to response improvement was 5.7 months … Zobraziť viac After a median follow-up of 58.6 months from the initiation of maintenance therapy, the PFS was significantly longer with TV as compared with the two other … Zobraziť viac Regarding hematological toxicity, 10 patients developed thrombocytopenia grade 3–4 in the TV arm, while only 2 patients developed grade 3–4 … Zobraziť viac Web27. jan 2024 · PETHEMA ALL-96 (patients aged <30 years) 28,i. Remission Induction Therapy: ... Refer to GRAALL-2005 regmen for timing and frequency of administration. … primary education spending by country