Olfm4 and cancer
Web10. jan 2007. · Overexpression of the olfactomedin 4 (OLFM4 GW112,/hGC−1) gene was recently reported to inhibit various apoptotic pathways and promote proliferation of … Web19. nov 2015. · Loss of olfactomedin 4 (OLFM4) gene expression is associated with the progression of human prostate cancer, but its role and the molecular mechanisms …
Olfm4 and cancer
Did you know?
WebProtein function (UniProt)i. Useful information about the protein provided by UniProt. May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leu kemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 ... Web19. nov 2015. · Loss of olfactomedin 4 (OLFM4) gene expression is associated with the progression of human prostate cancer, but its role and the molecular mechanisms involved in this process have not been ...
Web21. mar 2024. · OLFM4 (Olfactomedin 4) is a Protein Coding gene. Diseases associated with OLFM4 include Atrophy Of Prostate and Colonic Benign Neoplasm.Among its related pathways are Innate Immune System and Adhesion.Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cadherin binding.An … Web01. jun 2016. · Development of colorectal cancer (CRC) is regulated by a series of genetic and microenvironmental alterations. Olfactomedin 4 (OLFM4) is a secreted glycoprotein that is highly expressed in the ...
Web27. maj 2024. · OLFM4 is highly expressed in polymorphonuclear bone marrow-derived inhibitory cells in colitis and colorectal cancer, its expression levels and cell populations are positively correlated with the ... WebOLFM4 expression has been studied in several tumor types including gastric, colorectal, lung, and endometrioid cancers where it has been suggested to be an independent …
Web02. maj 2024. · OLFM4 promotes tumor cell proliferation by activating STAT3 and accelerating cell-cycle progression in gastric cancer 22 and pancreatic cancer. 25 …
hiram the widow\u0027s son sent to king solomonWebChronic inflammatory bowel disease (IBD) is strongly associated with the development of colitis-associated tumorigenesis (CAT). Despite recent advances in the understanding of … homes for sale in rockwood school districtWebNational Center for Biotechnology Information homes for sale in rockwood manitobaWeb10. dec 2024. · Olfactomedin 4 (OLFM4) was first cloned from human hematopoietic myeloid cells and is endogenously expressed in neutrophils, the gastrointestinal tract, and the prostate.1 It is a member of a well-conserved, olfactomedin domain–containing glycoprotein family and plays important roles in innate immunity, inflammation, and … homes for sale in rock springs wyomingWebAs a target gene of important signal pathways implicated in cancer and inflammation, OLFM4 may emerge as a potential therapeutic target for these diseases. Recent publications have also reported increased expression of OLFM4 in gastrointestinal cancer ( 10 – 13 ) and inflammatory disease including inflammatory bowel disease ( 14 ) and H ... hiram the skillful builderWeb15. mar 2024. · Low expression of OLFM4 promoted lymph node and distant metastasis resulting in a poor prognosis of triple-negative breast cancer patients and low expression of OLFM4 in early gastric cancer was ... homes for sale in rockwell ncWebPancreatic ductal adenomcarcinoma (PDAC) is one of the most lethal forms of cancer with a 5-year survival rate of 8%. To determine the composition of different cell types in PDAC, we performed ... hiram to marietta