TīmeklisFerroptosis is one of the forms of programmed cell death. Besides being a necessary micronutrient, iron is the key element that initiates ferroptosis in the cell. Intracellular unstable iron accumulation increases the amount of intracellular ROS, especially by the peroxidation of unsaturated membrane phospholipids. Insufficient antioxidant … Tīmeklis2008. gada 1. maijs · The normal, low-level diffusion of hydrogen peroxide into iron-rich lysosomes causes the slow formation of lipofuscin in long-lived postmitotic cells, …
(PDF) Lysosomes in iron metabolism, ageing and apoptosis
TīmeklisDownload scientific diagram The stable nitroxide TEMPOL potently inhibited the RdRp by causing disassembly of its Fe-S clusters and blocked viral replication in cell culture models of SARS-CoV-2 ... Tīmeklis2024. gada 16. apr. · Autophagy is a dynamic process that relies on the formation and maturation of specific membrane structures, such as phagophores, … nishchay foundation
Acute Iron Deprivation Reprograms Human Macrophage …
Tīmeklis2016. gada 12. aug. · Ferroptosis is an iron-dependent form of regulated necrosis. It is implicated in various human diseases, including ischemic organ damage and … Tīmeklis2024. gada 17. dec. · Ferroptosis is one of the forms of programmed cell death. Besides being a necessary micronutrient, iron is the key element that initiates ferroptosis in … TīmeklisSubsequent inflammation caused by the Interlukin-6 response triggers a hepcidin surge which decreases the expression of Ferroportin and increases the ferrophagy via Transferrin 1 receptor ... nish chandran suncorp