WebEthyl carbamate, or urethane (Fig. 7.5A), is the notional parent compound of a very large series of polymerizable substances derived from isocyanates, R─N═C═O (see also 10§6.3). In principle, and ignoring the chemistry that leads to the formation of such derivatives, the urethane unit can be extended by modifying the ester part ...
Hazards of urethane (ethyl carbamate): a review of the literature
Ethyl carbamate (also called urethane) is an organic compound with the formula CH3CH2OC(O)NH2. It is an ester of carbamic acid and a white solid. Despite its name, it is not a component of polyurethanes. Because it is a carcinogen, it is rarely used, but naturally forms in low quantities in many types of … See more It is produced industrially by heating urea and ethyl alcohol. It arise also by the action of ammonia on ethyl chloroformate. See more Biomedical applications Ethyl carbamate has been used as an antineoplastic agent and for other medicinal … See more Ethyl carbamate is not acutely toxic to humans, as reflected by its use as a medicine. Acute toxicity studies show that the lowest fatal … See more Other carbamates include methyl carbamate, butyl carbamate, and phenyl carbamate (m. p. 149–152 °C), which can also be prepared from the corresponding chloroformate and ammonia. These esters are white, crystalline solids at room temperature. … See more The widespread presence of ethyl carbamate in alcoholic beverages was discovered during the mid-1980s. To raise public awareness … See more The concerns raised by the toxicological aspects of EC together with the low concentration levels (µg/L) found in wines, as well as the … See more • Carbamate • Methyl carbamate See more WebGeorge A. Vogler, in The Laboratory Rat (Second Edition), 2006 6. Urethane (Ethyl Carbamate) Urethane (ethyl carbamate) is a mutagenic, carcinogenic and hepatotoxic anesthetic used to provide anesthesia adequate for surgical procedures lasting up to 8 or more hours (Maggi and Meli, 1986a-c; Field et al. 1993).Hara and Harris (2002) … clinical child psychology definition
Urethane - NIST
WebUrethane may be released to the environment in various waste streams. If released to the atmosphere, urethane is expected to exist solely as a vapor in the ambient atmosphere. ... The components, for example, diethyl carbonate and ethylenediamine, are mixed and heated gently to afford ethyl N-2-aminoethylcarbamate (Equation (80)) < 34GEP676049 ... WebIUPAC Standard InChIKey: JOYRKODLDBILNP-UHFFFAOYSA-N Copy CAS Registry Number: 51-79-6 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file The 3d structure may be viewed using Java or Javascript. Other names: Carbamic acid, ethyl ester; Ethyl carbamate; Ethyl urethane; O … WebUrethane (ethyl carbamate) is used alone or in combination with other drugs to produce anaesthesia in laboratory animals. Although originally studied as a potential phytocide, urethane demonstrated antineoplastic properties when administered to rats with the Walker rat carcinoma 256. Subsequent trials in humans led to its use as a ... bobbins care home