Cisplatin chemical formula
WebChemical Name cis-Diaminodichloroplatinum Biological Activity Potent anticancer agent that blocks DNA synthesis. Induces apoptosis via p53-dependent and -independent mechanisms. Inhibits X-linked inhibitor of apoptosis protein (XIAP) expression and activates caspase-3. In certain glioma cell lines, sensitizes cells to TNF-α-induced apoptosis. WebThe active ingredient, cisplatin, is a yellow to orange crystalline powder with the molecular formula PtCl 2 H 6 N 2 , and a molecular weight of 300.1. Cisplatin is a heavy 1 Reference ID:...
Cisplatin chemical formula
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WebCisplatin (cis-diaminedichloroplatinum [II]) is a platinum-based chemotherapy drug that has been FDA-approved for treatment of a variety of cancers including sarcomas, small-cell lung cancer, ovarian cancer, lymphomas, and germ cell tumors. WebSep 15, 2024 · Cisplatin – Generic, Platinol® DRUG CLASS Antineoplastic Agents, Alkylating Agents COMPLETE LABELING Product labeling at DailyMed, National Library …
WebJun 13, 2005 · Chemical Formula Cl 2 H 6 N 2 Pt Synonyms CDDP Cis-DDP Cisplatin cisplatino Pharmacology Indication For the treatment of metastatic testicular tumors, … WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in …
WebApr 10, 2024 · Acetic acid glacial (99.7%), cisplatin (cis-dichlorodiammine platinum (II), 99.9%), (3- (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), Dulbecco’s Modified Eagle’s Medium—high-glucose cell growth medium (DMEM-HG), 1:1 mixture of Dulbecco’s Modified Eagle’s Medium and Ham’s F12 cell growth medium (DMEM/F12 … WebCisplatin Cl2H6N2Pt CID 5460033 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
WebFeb 28, 2024 · The most common chemotherapeutic agents are based on platinum complexes, among which the first-in-class drug is cisplatin [ 10, 11, 12 ]. Transport across the cancer cell membrane is the first step for cisplatin therapy to be successful.
WebSep 1, 2024 · Cisplatin for injection has been administered at 50 mg/m 2 to 70 mg/m 2 intravenously per cycle once every 3 to 4 weeks. For heavily pretreated patients, an initial dose of 50 mg/m 2 per cycle repeated every 4 weeks is recommended. Other doses and combination in regimens have been used. Dose Modifications great grandparents clip artCisplatin interferes with DNA replication, which kills the fastest proliferating cells, which in theory are cancerous. Following administration, one chloride ion is slowly displaced by water to give the aquo complex cis-[PtCl(NH3)2(H2O)] , in a process termed aquation. Dissociation of the chloride is favored inside the cell because the intracellular chloride concentration is only 3–20% of the approxi… flix python christmasWebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 … great grandparents christmas ornamentsWebCisplatin is a chemotherapy drug used to treat several different types of cancer. The chemical formula is Pt (NH3)3Cl2 a) How many atoms of hydrogen are contained in 85 … flixpyWebCisplatin, chemical structure, molecular formula, Reference Standards Cl 2 H 6 N 2 Pt 300.04 Platinum,diamminedichloro-, ( SP -4-2)-. cis -Diamminedichloroplatinum [ 15663-27-1 ]. »Cisplatin contains not less than 98.0percent and not more than 102.0percent of Cl 2 H 6 N 2 Pt,calculated on the anhydrous basis. great grandparents clipartWebJan 16, 2024 · The chemical formula of the compound is trans-PtCl 2 (NH 3) 2. It exists as a yellow solid with very low water solubility. However, … great grandparents irish passportWebCisplatin (Ingredient) Chemical formula: Cl2H4N2Pt Drugbank ID: DB00515 ATC code: L01XA01. The information below refers to products available in the United States that … flixr coach