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Carboplatin monotherapy

WebSep 14, 2024 · Since many patients begin chemotherapy with such a combination, and since platinum agents such as carboplatin tend to cause significant problems with bone … WebMar 4, 2024 · The primary objectives of this study are to evaluate the safety and tolerability of bemarituzumab monotherapy and combination with other anti-cancer therapies, and to determine the recommended phase 3 dose of bemarituzumab in combination with other anti-cancer therapies. Study Design Go to Resource links provided by the National Library of …

A phase II study of carboplatin AUC-10 guided by positron ... - PubMed

http://mdedge.ma1.medscape.com/hematology-oncology/article/35763/breast-cancer/platinum-monotherapy-active-against-metastatic WebApr 16, 2024 · A randomized, phase 2 trial of carboplatin plus pemetrexed (Alimta, Eli Lilly) with or without pembrolizumab showed significantly better rates of response and longer progression-free survival... pneu moto online https://prismmpi.com

Prostate Cancer Treatment Regimens - Cancer Therapy Advisor

WebFeb 1, 2024 · Preferred Regimens. Carboplatin + Paclitaxel 8-10,d. Premedication is required. Day 1: Paclitaxel 175mg/m 2 IV over 3 hours, followed by: Day 1: Carboplatin AUC 5 IV over 30 minutes. Repeat cycle ... WebFeb 24, 2024 · This is a prospective, randomised, open-label, positive-controlled study to investigate the efficacy and safety of Osimertinib plus Carboplatin/Pemetrexed versus Osimertinib monotherapy in metastatic EGFRm NSCLC patients with EGFRm persistence in ctDNA at 3 weeks after first-line therapy with Osimertinib. Study Design Go to WebJun 1, 2024 · This randomized clinical trial shows that compared with every-3-weeks or weekly carboplatin-paclitaxel regimens, single-agent carboplatin was less active with … bank durks

Trial Evaluating the Efficacy of CARBOPLATIN in Metastatic …

Category:NRG-GY019: A Randomized Phase III, Two-Arm Trial of Paclitaxel ...

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Carboplatin monotherapy

Merck and Eisai Provide Update on Phase 3 Trials of KEYTRUDA ...

Use in Cancer. Carboplatin is approved to be used alone or with other drugs to treat: Ovarian cancer that is advanced. It is used with other chemotherapy as first-line treatment. It is used alone as palliative treatment for disease that has recurred (come back) after earlier chemotherapy. See more Carboplatin is approved to be used alone or with other drugsto treat: 1. Ovarian cancer that is advanced. It is used with other chemotherapy as first-line treatment. It is used alone as palliative treatment for disease that has … See more Definition from the NCI Drug Dictionary- Detailed scientific definition and other names for this drug. MedlinePlus Information on Carboplatin- A lay language summary … See more Find Clinical Trials for Carboplatin- Check for trials from NCI's list of cancer clinical trials now accepting patients. See more WebJul 13, 2024 · This is not an exhaustive list; it includes regimens that are considered by the authors and editors to be commonly used and important for the care of patients with non-small cell lung cancer. Additional regimens may be added over time, particularly as treatment for non-small cell lung cancer evolves.

Carboplatin monotherapy

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WebAug 29, 2024 · Study Description Go to Brief Summary: The investigators propose a phase II study to evaluate the efficacy of carboplatin monotherapy in the tumor subgroup of metastatic castration-resistant prostatic carcinomas with somatic abnormality in the Homologous Recombination (HR) pathway. WebIntroduction: Carboplatin monotherapy for metastatic seminoma at a dose of AUC-10 has shown promising activity. Three or four cycles have been given with most haematological side-effects seen with the 4th cycle. An early response might allow de-escalation of therapy.

WebCarboplatin, Letrozole, Paclitaxel Description This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum. WebNCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine.

WebMay 16, 2024 · Patients received 21-day cycles of gemcitabine (1000 mg/m2body surface area, administered intravenously on days 1 and 8 of each cycle), plus either carboplatin (area under the curve of 4·5 mg/mL per min administered intravenously) or cisplatin (70 mg/m2body surface area administered intravenously) on day 1 of each cycle with either … WebJun 19, 2024 · Detailed Description: This is a Phase 1/2, open-label, prospective, multi-center, single-arm study to establish the safety and feasibility of blood-brain-barrier …

WebApr 14, 2024 · Abstract. The Bromodomain and Extra-Terminal (BET) Domain proteins facilitate the development of many human cancers via epigenetic regulation. BET inhibitors may be effective in reversing platinum resistance in ovarian cancer (OC) and may generate synthetic lethality with ARID1A loss. PLX2853 is an orally active, small molecule inhibitor …

WebMar 30, 2024 · Time-to-treatment-failure (TTF) is the interval from chemotherapy initiation to premature discontinuation. We evaluated TTF based on age. Methods Pooled analyses were conducted with, first-line chemotherapy trials for advanced non-small cell lung cancer (CALGB 9730, 30203, and 30801). bank durch ibanWebJul 30, 2024 · This trial will use olaparib or carboplatin as initial therapy with crossover to the alternate or second-line drug after first progression for patients with tumors … bank duration gap formulaWebOct 21, 2024 · INTRODUCTION The following material represents a subset of chemotherapy and immunotherapy regimens that are used for the treatment of women with gynecologic cancers. This is not an exhaustive list; it includes regimens that are considered by the authors and editors to be commonly used and important for the care of patients … pneu mythosWebFeb 26, 2024 · Carboplatin (AUC 2) was given weekly for 4 weeks of a 6-week cycle in combination with 1mg daily dexamethasone. Results: Sixty-four carboplatin-treated … pneu neolin avisWebJan 15, 2016 · In this retrospective analysis single agent carboplatin shows comparable efficacy to historical multiagent chemotherapy for the treatment of patients with … bank dwg indirWebNov 1, 2024 · Carboplatin/Paclitaxel 2-6,b. Premedication is required for Paclitaxel. Day 1: Paclitaxel 175mg/m 2 IV over 3 hours, followed by: Day 1: Carboplatin AUC 6-7.5 IV … bank duta sukapuraWebRe-treatment with single-agent platinum has long been considered standard therapy for patients with platinum-sensitive disease, and, based on its favorable therapeutic profile, carboplatin has become the treatment agent of choice. High response rates are seen with platinum agents used in combination with paclitaxel or gemcitabine. pneu nissan np300