Web288 rows · Apr 1, 2024 · However, there are pharmaceutical dosage forms which, in principle, should never be crushed. Amongst these are those that come with an enteric … WebFeb 1, 2024 · frequent urge to urinate. indigestion. lower back or side pain. muscle spasm. pain or tenderness around the eyes and cheekbones. shakiness in the legs, arms, hands, or feet. shortness of breath or troubled breathing. sneezing. stomach upset.
Zoryve (roflumilast): Basics, Side Effects & Reviews
WebFeb 15, 2014 · Roflumilast has been studied only in patients who have taken it for up to 52 weeks. 2, 3 Psychiatric effects, including suicidality, have been reported with … WebJan 13, 2024 · Rare side effects of Roflumilast include: none. Seek medical care or call 911 at once if you have the following serious side effects: Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors; people fall flat game
National Center for Biotechnology Information
WebSep 25, 2024 · The beneficial effects of roflumilast on cognition are believed to be mediated through the above-mentioned cellular effects. Recently, Jabaris et al had shown that roflumilast has improved the short and long-term memory in rodents. Several lines of evidence indicate that targeting PDE-4 inhibition might offer novel approaches in the … Webeslicarbazepine acetate will decrease the level or effect of roflumilast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration not recommended; strong cytochrome P450 enzyme inducers decrease systemic exposure to roflumilast and may reduce the therapeutic effectiveness. etravirine. WebRoflumilast was generally well tolerated, with diarrhea, nausea, and headache the most common adverse events seen in clinical trials, although it has also been associated with … to-fast-properties